PEPTIC-DUODENTAL ULCERS
What is Peptic-Duodenal Ulcer?
A peptic ulcer is a sore on the lining of the stomach or duodenum, which is the beginning of the small intestine.One cause of peptic-duodenal ulcer is bacterial infection, but some ulcers are caused by long-term use of non-steroidal anti-inflammatory agents (NSAIDs), like aspirin and ibuprofen. In a few cases, cancerous tumors in the stomach or pancreas can cause ulcers.
What is H. Pylori?
Helicobacter pylori (H. pylori) is a type of bacteria. Researchers believe that H. pylori is responsible for the majority of peptic ulcers.
H. pylori infection is common in the United States: About 20 percent of people under 40 years old and half of those over 60 have it. Most infected people, however, do not develop ulcers.
How Does H. Pylori Cause a Peptic Ulcer?
H. pylori weakens the protective mucous coating of the stomach and duodenum, which allows acid to get through to the sensitive lining beneath. Both the acid and the bacteria irritate the lining and cause a sore, or ulcer.
What are the Symptoms of an Ulcer?
Abdominal discomfort is the most common symptom. This discomfort usually is a dull gnawing ache that comes and goes for several days or weeks and occurs 2 to 3 hours after a meal.
How is an H. Pylori-Related Ulcer Diagnosed?
To see whether symptoms are caused by an ulcer, the doctor may do an upper gastrointestinal (GI) series or an endoscopy. An upper GI series is an x ray of the esophagus, stomach, and duodenum.
H. pylori is diagnosed through blood, breath, stool, and tissue tests. Blood tests are most common. They detect antibodies to H. pylori bacteria.
How are H. Pylori Peptic Ulcers Treated?
H. pylori peptic ulcers are treated with drugs that kill the bacteria, reduce stomach acid, and protect the stomach lining. Antibiotics are used to kill the bacteria. Two types of acid-suppressing drugs might be used: H2 blockers and proton pump inhibitors.
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